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Atypical teratoid/rhabdoid tumor, BAF-47 immunohistochemical staining with arrow

Last updated on Thursday, April 2 2009 by jdmiles

Atypical teratoid/rhabdoid tumor, BAF-47 immunohistochemical staining with arrow

Atypical teratoid/rhabdoid tumors are defined by mutations in the INI1 gene. BAF-47 is recognized as the protein product of the INI1 gene, and therefore is diagnostic by its absence within tumor cells (note positive internal control reactivity with non-neoplastic blood vessels - unnecessarily large green arrow).

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