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H & E

Last updated on Saturday, April 4 2009 by jdmiles

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H&E is short for "Hematoxylin and Eosin."  The H&E staining method is the most commonly used stain in neuropathology.  It is a simple stain, and provides an excellent first look at the tissue of interest.

Hematoxylin as a basic dye, and has an affinity for basophilic structures. It stains these structures with a bluis-purple color.  Basophilic structures include the cell nucleus and ribosomes.  

Eosin is a pink acidic dye.  Cytoplasm and protein tend to be eosinophilic.