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Adverse effects of AEDs 01

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of phenytoin?

 
        A) Peripheral neuropathy
 
        B) Visual changes
 
        C) Weight loss
 
        D) Blindness
 
        E) Nervousness
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) peripheral neuropathy

This answer is correct.


Side effects of phenytoin include coarsening of the facies, peripheral neuropathy, gum hyperplasia, and hirsutism.  (See References)

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B) visual changes

This answer is incorrect.


Visual changes is a hallmark side effect of ethosuximide, but is less characteristic of phenytoin.  (See References)

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C) weight loss

This answer is incorrect.


Weight loss is a hallmark side effect of topiramate and felbamate, but is less characteristic of phenytoin.  (See References)

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D) blindness

This answer is incorrect.


Blindness is a hallmark side effect of vigabatrin, but is less characteristic of phenytoin.  (See References)

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E) nervousness

This answer is incorrect.


Nervousness is a hallmark side effect of tiagabine, but is less characteristic of phenytoin.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 01
Question ID: 12080701
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 11400480

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