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Adverse effects of AEDs 01

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of phenytoin?

 
        A) Weight loss
 
        B) Visual field defects
 
        C) Pancreatitis
 
        D) Peripheral neuropathy
 
        E) Insomnia
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) weight loss

This answer is incorrect.


Weight loss is a hallmark side effect of topiramate and felbamate, but is less characteristic of phenytoin.  (See References)

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B) visual field defects

This answer is incorrect.


Visual field defects is a hallmark side effect of vigabatrin, but is less characteristic of phenytoin.  (See References)

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C) pancreatitis

This answer is incorrect.


Pancreatitis is a hallmark side effect of valproate, but is less characteristic of phenytoin.  (See References)

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D) peripheral neuropathy

This answer is correct.


Side effects of phenytoin include hirsutism, peripheral neuropathy, gum hyperplasia, and coarsening of the facies.  (See References)

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E) insomnia

This answer is incorrect.


Insomnia is a hallmark side effect of felbamate and vigabatrin, but is less characteristic of phenytoin.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 01
Question ID: 12080701
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 11400480

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