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Paraneoplastic Syndromes 02

Topic: Adult

Created on Sunday, January 6 2008 by jdmiles

Last modified on Sunday, January 6 2008.

Several antibodies are associated with paraneoplastic syndromes, and with characteristic neoplasms. Which of the following antibodies is not typically associated with small cell lung cancer (SCLC)?

 
        A) Anti-CAR
 
        B) Anti-Ri
 
        C) Anti-Hu
 
        D) Anti-MysB
 
        E) Antiamphiphysin
 

 


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This question was created on January 06, 2008 by jdmiles.
This question was last modified on January 06, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Anti-CAR

This answer is incorrect.


Anti-CAR antibodies are associated with SCLC and other cancers.  (See References)

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B) Anti-Ri

This answer is incorrect.


Anti-Ri is associated with breast and gynecologic cancers, and with SCLC.  (See References)

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C) Anti-Hu

This answer is incorrect.


Anti-Hu is associated with SCLC and neuroblastoma.  (See References)

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D) Anti-MysB

This answer is incorrect.


Anti-MysB antibodies are associated with SCLC.  (See References)

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E) Antiamphiphysin

This answer is correct.


Antiamphiphysin is associated with breast cancer, but not usually with SCLC.  (See References)

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References:

1. Dalmau, J.O., and Posner, J.B. (1999). "Paraneoplastic syndromes." Arch Neurol, 56(4) 405-8. (PMID:10199327)
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adult
Paraneoplastic Syndromes 02
Question ID: 010608163
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 01/06/2008
Modified: 01/06/2008
Estimated Permutations: 7200

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