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Adverse effects of AEDs 01

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of phenytoin?

 
        A) Dupytren's contractures
 
        B) Renal calculi
 
        C) Hepatoxicity
 
        D) Peripheral neuropathy
 
        E) Hypersalivation
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Dupytren's contractures

This answer is incorrect.


Dupytren's contractures is a hallmark side effect of barbiturates, but is less characteristic of phenytoin.  (See References)

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B) renal calculi

This answer is incorrect.


Renal calculi is a hallmark side effect of zonisamide and topiramate, but is less characteristic of phenytoin.  (See References)

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C) hepatoxicity

This answer is incorrect.


Hepatoxicity is a hallmark side effect of felbamate, but is less characteristic of phenytoin.  (See References)

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D) peripheral neuropathy

This answer is correct.


Side effects of phenytoin include coarsening of the facies, gum hyperplasia, hirsutism, and peripheral neuropathy.  (See References)

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E) hypersalivation

This answer is incorrect.


Hypersalivation is a hallmark side effect of benzodiazepines, but is less characteristic of phenytoin.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 01
Question ID: 12080701
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 11400480

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