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Acute neuronal necrosis - cerebellum

Last updated on Tuesday, September 2 2008 by gliageek

Acute neuronal necrosis - cerebellum

Eosinophilic neuronal degeneration selectively involving Purkinje cells.

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Acute neuronal necrosis cerebellum 2

Acute neuronal necrosis cerebellum 2
The cells circled in green in this image are Purkinje cells. Purkinje cells are found in the cerebellum between the granule cell layer (dark blue cells on the left) and the molecular layer (the big pink area taking up most of the right side of this picture)...

Normal Cerebellum

Normal Cerebellum
For contrast, this is an H&E stain of normal cerebellum, with an unnecessarily large red arrow indicating a normal Purkinje cell. Note that the Purkinje cells are not bright red.

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