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Amyloid angiopathy involving temporal artery, H&E stain x 20

Last updated on Thursday, April 9 2009 by gliageek

Amyloid angiopathy involving temporal artery, H&E stain x 20

Hyalin thickening of the arterial wall with loss of normal cellular components. Unlike leptomeningeal blood vessels where amyloid angiopathy is nearly always due to vascular involvement by beta amyloid, temporal arteries demonstrate vascular amyloid secondary to proteins associated with systemic amyloidoses. This patient was subsequently found to have multiple myeloma with systemic light chain amyloidosis.

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