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Atypical Teratoid Rhabdoid Tumor, intraoperative smear preparation x 600 (H&E stain). with arrow

Last updated on Thursday, April 2 2009 by jdmiles

Atypical Teratoid Rhabdoid Tumor, intraoperative smear preparation x 600 (H&E stain). with arrow

Atypical Rhabdoid/Teratoid Tumors (ATRTs) are a type of embryonal tumors seen in infants and children. They are rare, malignant, and most commonly arise in the posterior fossa, although they can arise elsewhere. The tumor cells have the morphology shown here. Cells have an eccentrically placed nucleus, prominent nucleoli and abundant cytoplasm which is eosinophilic and granular. The unnecessarily large red arrow points to an intracytoplasmic inclusion composed of vimentin intermediate filaments.

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