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Example of trichrome stain

Last updated on Friday, February 6 2009 by jdmiles

This is an example of a muscle specimen stained with Gomori trichrome. On trichrome, muscle typically shows up as a greenish blue (or in this case, just green). This particular muscle biopsy is an example of nemaline rod myopathy. The nemaline rods are tiny dark spots visible in most of the muscle fibers. This is an example of something we'd see on trichrome that we wouldn't see on H&E.

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Gomori Trichrome Nemaline Rods 2
A Gomori trichrome stain of skeletal muscle from an individual with nemaline rod myopathy. The rods themselves show up as small dark dots on trichrome (highlighted here by the red circles). Note that these rods typically do not show up on H&E staining.