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Pathology in Ischemic Stroke 01

Topic: Pathology

Created on Saturday, February 24 2007 by jdmiles

Last modified on Saturday, February 24 2007.

A patient presents with an acute ischemic stroke and dies 18 hours after onset of symptoms. Of the following choices, which is most likely to be seen on pathology?

A) Gliotic scar at infarct edges

B) Eosinophilic changes in neurons

C) Appearance of macrophages

D) Liquefaction necrosis

E) Capillary proliferation

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This question was created on February 24, 2007 by jdmiles.
This question was last modified on February 24, 2007.

ANSWERS AND EXPLANATIONS

A) gliotic scar at infarct edges

This answer is incorrect.

Appearance of cavitation, liquefaction necrosis, and the formation of a glial scar at the edge of the infarct occur months to years after the infarct. (See References)


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B) eosinophilic changes in neurons

This answer is correct.

Pathology findings seen 12-24 hours after an acute ischemic stroke include tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons. (See References)


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C) appearance of macrophages

This answer is incorrect.

Appearance of macrophages, capillary proliferation, and the appearance of reactive astrocytes at the edge of the infarct occur 2 days to 2 weeks after the infarct. (See References)


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D) liquefaction necrosis

This answer is incorrect.

Appearance of cavitation, liquefaction necrosis, and the formation of a glial scar at the edge of the infarct occur months to years after the infarct. (See References)


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E) capillary proliferation

This answer is incorrect.

Appearance of macrophages, capillary proliferation, and the appearance of reactive astrocytes at the edge of the infarct occur 2 days to 2 weeks after the infarct. (See References)


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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier, Philadelphia.


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pathology
Pathology in Ischemic Stroke 01
Question ID: 022407199
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/24/2007
Modified: 02/24/2007
Estimated Permutations: 5400