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Subependymal Giant Cell Astrocytoma, Neurofilament immunohistochemical staining

Last updated on Wednesday, April 8 2009 by gliageek

Subependymal Giant Cell Astrocytoma, Neurofilament immunohistochemical staining

Epithelioid cells within Subependymal giant cell astrocytomas often react strongly with antibodies to neurofilaments. This admixture of cell types strengthens the biologic identity with tuberous sclerosis, and has lead to the suggestion that these tumors be re-named "subependymoma giant cell tumors". The reason that this designation has not been used more widely may relate to the difficulty in pronunciation SEGT compared with SEGA.

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