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Medulloblastoma, large cell anaplastic variant, H&E stain slide x 400

Last updated on Thursday, April 2 2009 by gliageek

Medulloblastoma, large cell anaplastic variant, H&E stain slide x 400

Approximately 10% of medulloblastomas will demonstrate anaplastic large cell features, characterized by enlarged nuclei with prominent nucleoli. Anaplastic Medulloblastomas are characterized by c-myc amplification and a more aggressive clinical course.

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