Cerebral Ischemia 01

Topic: Pathology

Created on Monday, November 26 2007 by jdmiles

Last modified on Monday, November 26 2007.

 
        A) Pigmented neurons in the substantia nigra
 
        B) Microglia
 
        C) Betz cells in the cerebral cortex
 
        D) Granule cells in the cerebellum
 
        E) Purkinje cells in the cerebellum
 

 

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This question was created on November 26, 2007 by jdmiles.
This question was last modified on November 26, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

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A) Pigmented neurons in the substantia nigra

This answer is incorrect.

The cell types in the brain that are most susceptible to hypoxia are the pyramidal cells in the CA1 area of the hippocampus, and the Purkinje cells from the cerebellum.

  (See References)

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B) Microglia

This answer is incorrect.

The cell types in the brain that are most susceptible to hypoxia are the pyramidal cells in the CA1 area of the hippocampus, and the Purkinje cells from the cerebellum.

Glial cells are more resistant to hypoxic injury than are neurons.

  (See References)

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C) Betz cells in the cerebral cortex

This answer is incorrect.

The cell types in the brain that are most susceptible to hypoxia are the pyramidal cells in the CA1 area of the hippocampus, and the Purkinje cells from the cerebellum.

With somewhat more severe hypoxic injury, laminar necrosis will occur in cerebral cortex layers III, V, and VI.

  (See References)

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D) Granule cells in the cerebellum

This answer is incorrect.

The cell types in the brain that are most susceptible to hypoxia are the pyramidal cells in the CA1 area of the hippocampus, and the Purkinje cells from the cerebellum.

With somewhat more severe hypoxic injury, laminar necrosis will occur in cerebral cortex layers III, V, and VI.

  (See References)

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---

E) Purkinje cells in the cerebellum

This answer is correct.

The cell types in the brain that are most susceptible to hypoxia are the pyramidal cells in the CA1 area of the hippocampus, and the Purkinje cells from the cerebellum.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)

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pathology
Cerebral Ischemia 01
Question ID: 112607090
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 11/26/2007
Modified: 11/26/2007
Estimated Permutations: 30240