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0 user entriesAdverse effects of AEDs 02
Topic:  PharmacologyCreated on Saturday, December 8 2007 by jdmiles Last modified on Saturday, December 8 2007. Which of the following is a hallmark side effect of barbiturates?
A)  Insomnia         B)  Peripheral neuropathy         C)  Paresthesias         D)  Hirsutism         E)  Weight gain  This question was created on December 08, 2007 by jdmiles. This question was last modified on December 08, 2007.
                                           ANSWERS AND EXPLANATIONS
 A)  insomnia
 This answer is incorrect.
Insomnia is a hallmark side effect of vigabatrin and felbamate, but is less characteristic of barbiturates.  (See References )
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 B)  peripheral neuropathy
 This answer is correct.
Side effects of barbiturates include Dupytren's contractures and peripheral neuropathy.  (See References )
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 C)  paresthesias
 This answer is incorrect.
Paresthesias is a hallmark side effect of topiramate, but is less characteristic of barbiturates.  (See References )
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 D)  hirsutism
 This answer is incorrect.
Hirsutism is a hallmark side effect of phenytoin, but is less characteristic of barbiturates.  (See References )
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 E)  weight gain
 This answer is incorrect.
Weight gain is a hallmark side effect of valproate and gabapentin, but is less characteristic of barbiturates.  (See References )
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         References:
 
| 1.  Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739) |  |  
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 Adverse effects of AEDs 02
 Question ID: 12080702
 Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
 Created:  12/08/2007
 Modified: 12/08/2007
 Estimated Permutations: 7551600
 
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