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Neurooncology 02

Topic: Pathology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

A 67 year-old man presents to the emergency department with new onset of seizures. MRI is suggestive of a mass lesion. A biopsy is performed, and a photomicrograph of the tissue obtained is shown above.
Of the following, which is the most likely diagnosis?

A) Normal cerebellum

B) Oligodendroglioma

C) Glioblastoma multiforme

D) Ependymoma

E) Schwannoma

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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

ANSWERS AND EXPLANATIONS

A) Normal cerebellum

This answer is incorrect.

This image shows disorganized, heterogeneous tissue with pseudopallisading and necrosis. The most likely diagnosis is glioblastoma multiforme (GBM). (See References)


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B) Oligodendroglioma

This answer is incorrect.

This image shows disorganized, heterogeneous tissue with pseudopallisading and necrosis. The most likely diagnosis is glioblastoma multiforme (GBM). (See References)


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C) Glioblastoma multiforme

This answer is correct.

This image shows disorganized, heterogeneous tissue with pseudopallisading and necrosis. The most likely diagnosis is glioblastoma multiforme (GBM). (See References)


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D) Ependymoma

This answer is incorrect.

This image shows disorganized, heterogeneous tissue with pseudopallisading and necrosis. The most likely diagnosis is glioblastoma multiforme (GBM). (See References)


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E) Schwannoma

This answer is incorrect.

This image shows disorganized, heterogeneous tissue with pseudopallisading and necrosis. The most likely diagnosis is glioblastoma multiforme (GBM). (See References)


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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)

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pathology
Neurooncology 02
Question ID: 120807157
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 16800

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