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Adverse effects of AEDs 07

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of valproate?

 
        A) Paresthesias
 
        B) Emotional changes
 
        C) Pancreatitis
 
        D) Hypersalivation
 
        E) Hyponatremia
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) paresthesias

This answer is incorrect.


Paresthesias is a hallmark side effect of topiramate, but is less characteristic of valproate.  (See References)

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B) emotional changes

This answer is incorrect.


Emotional changes is a hallmark side effect of tiagabine, but is less characteristic of valproate.  (See References)

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C) pancreatitis

This answer is correct.


Side effects of valproate include weight gain, tremor, hair loss, pancreatitis, hyperammonemia, hepatotoxicity, and thrombocytopenia.  (See References)

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D) hypersalivation

This answer is incorrect.


Hypersalivation is a hallmark side effect of benzodiazepines, but is less characteristic of valproate.  (See References)

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E) hyponatremia

This answer is incorrect.


Hyponatremia is a hallmark side effect of oxcarbazepine and carbamazepine, but is less characteristic of valproate.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 07
Question ID: 12080707
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 12558000

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