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Pelizaeus Merzbacher disease, Co

Pelizaeus Merzbacher disease, Co
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This image shows a coronal section through a gross brain specimen from someone who had Pelizaeus Merzbacher disease. There is demyelination of the white matter (blue), with sparing of the subcortical U-fibers (green). This resulting appearance is usually refered to as tigroid, because of the supposed resemblance to tiger stripes.

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