NADH - Example of pathological f

This is a sample of skeletal muscle stained for NADH. This muscle is denervated. The pale areas in the center of the fibers are targets. The unnecessarily large green arrow points to a target. It may be impossible to distinguish between targets, which are markers of denervation, and cores, which are seen in myopathy. It may also be an unimportant issue, as other features typically suggest neuropathy or myopathy.