Angiocentric Glioma

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Angiocentric Glioma

Last updated on Wednesday, September 10 2008 by jdmiles

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Angiocentric Glioma, high power H&E stain
Not surprisingly, the angiocentric glioma is characterized by perivascular accumulation of cells such as is demonstrated in this photograph. The resemblance of the structures to perivascular pseudo-rosettes has lead some to believe that the angiocentric glioma may represent cortically based ependymoma.

Angiocentric glioma, synaptophysin immunohistochemical staining x 20
This low power view of the cerebral cortex highlighted with synaptophysin staining demonstrates the striking angiocentricity of this glial tumor

Angiocentric glioma, H&E stain x 20
This low power overview of the cerebral cortex demonstrates the angiocentric spread of this glial tumor.

Angiocentric glioma, H&E stain x400
Not surprisingly, the angiocentric glioma is characterized by perivascular accumulation of cells such as is demonstrated in this photograph. The resemblance of the structures to perivascular pseudo-rosettes has lead some to believe that the angiocentric glioma may represent cortically based ependymoma.

Angiocentric glioma, vimentin immunohistochemical staining
Angiocentric tumor localization within the cerebral cortex is most easily demonstrated with vimentin immunohistochemical staining.