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Glioblastoma multiforme, small cell variant, H&E stain x 200

Last updated on Friday, April 3 2009 by gliageek

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Glioblastoma multiforme, small cell variant, H&E stain x 200
Glioblastomas composed predominantly of small undifferentiated glial elements must be distinguished from anaplastic oligodendrogliomas. The presence of necrosis with peripheral palisading of tumor cells is very useful in this regard. Small cell glioblastoma is often demonstrate EGFR amplification.