The FrontalCortex question bank can help you study for the neurology boards.

Tumors I: Overview

Last updated on Monday, April 20 2009 by gliageek

peer review status unavailable
rating unavailable

General principles of neoplasia are applicable to CNS tumors

1.The neoplastic cell must have a growth advantage within the microenvironment. Therefore, tumor cells tend to phenotypically resemble cells normally present within the CNS.
2.The chance of transformational events depends on the number of replicating cells "at risk"
3.Once transformation is established, mutational events leading to increased growth advantage correlate with decreased cellular differentiation and more aggressive behavior.
4.Morbidity and mortality is related to invasion and metastasis. Here CNS tumors differ significantly from systemic cancer in that invasion with compression and/or destruction of normal structures is critical, while metastases are unusual, and largely irrelevant to the outcome in these patients.

Categories (tags) users associate with this resource what is this?
Click on a tag to find related images, videos, MCQs, and other resources.
Check the boxes next to the tags you consider relevant or enter your own tags in the field below.
You must be logged in to edit tags.
Top 5 tags for this item:
more tags:
new tag:

0 user entries
Please log in if you'd like to add a comment.