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Gomori Trichrome, showing inclusion bodies

Last updated on Friday, September 26 2008 by jdmiles

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Gomori Trichrome, showing inclusion bodies
The Gomori trichrome stain is a beautiful and efficient way to visualize muscular pathology which do not show well on H&E staining. For example, this specimen shows a biopsy of skeletal muscle from a patient with inclusion body myositis (IBM). The trichrome stain allows the visualization of the rimmed vacuoles that are the hallmark of this disease. These vacuoles would be harder to see on H&E.