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Neurodegen 02

Topic: Anatomy

Created on Sunday, February 8 2009 by gliageek

Last modified on Sunday, February 8 2009.


Courtesy of Dr. Mark Cohen

This pattern of spinal cord damage is most consistent with which of the following diseases?

 
        A) Tabes dorsalis
 
        B) Ataxia-telangiectasia
 
        C) ALS
 
        D) Fredreich ataxia
 
        E) Subacute combined degeneration
 

 


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This question was created on February 08, 2009 by gliageek.
This question was last modified on February 08, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Tabes dorsalis

This answer is incorrect.


Spinocerebellar tracts are generally spared in Tabes dorsalis  (See References)

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B) Ataxia-telangiectasia

This answer is incorrect.


Spinal cord degeneration generally restricted to posterior columns, especially gracile tracts  (See References)

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C) ALS

This answer is incorrect.


ALS would show corticospinal degeneration, both laterally and anteriorly  (See References)

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D) Fredreich ataxia

This answer is correct.


Combined spinocerebellar and posterior column degeneration is characteristic of Fredreich ataxia  (See References)

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E) Subacute combined degeneration

This answer is incorrect.


Though there is variability, the posterior columns and corticospinal tracts are usually most severely affected  (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
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anatomy
Neurodegen 02
Question ID: 020809081
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/08/2009
Modified: 02/08/2009
Estimated Permutations: 120

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