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Atypical teratoid/rhabdoid tumor, BAF-47 immunohistochemical staining

Last updated on Tuesday, March 31 2009 by gliageek

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Atypical teratoid/rhabdoid tumor, BAF-47 immunohistochemical staining
Atypical teratoid/rhabdoid tumors are defined by mutations in the INI1 gene. BAF-47 recognized as the protein product of the INI1 gene, and therefore is diagnostic by its absence within tumor cells (note positive internal control reactivity with non-neoplastic blood vessels).