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Paraneoplastic Syndromes 01

Topic: Adult

Created on Sunday, January 6 2008 by jdmiles

Last modified on Sunday, January 6 2008.

Of the following antibodies, which is most commonly associated with paraneoplastic limbic encephalitis?

 
        A) Anti-Tr
 
        B) Anti-Ta
 
        C) Anti-Hu
 
        D) Anti-Yo
 
        E) Anti-CV2
 

 


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This question was created on January 06, 2008 by jdmiles.
This question was last modified on January 06, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) anti-Tr

This answer is incorrect.


Anti-Hu antibodies are found in approximately 35% of patients with paraneoplastic limbic encephalitis. Approximately 20% have anti-Ta, and 40% have no diagnostic antibodies or uncharacterized antibodies.  (See References)

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B) anti-Ta

This answer is incorrect.


Anti-Hu antibodies are found in approximately 35% of patients with paraneoplastic limbic encephalitis. Approximately 20% have anti-Ta, and 40% have no diagnostic antibodies or uncharacterized antibodies.   (See References)

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C) anti-Hu

This answer is correct.


Anti-Hu antibodies are found in approximately 35% of patients with paraneoplastic limbic encephalitis. Approximately 20% have anti-Ta, and 40% have no diagnostic antibodies or uncharacterized antibodies.   (See References)

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D) anti-Yo

This answer is incorrect.


Anti-Hu antibodies are found in approximately 35% of patients with paraneoplastic limbic encephalitis. Approximately 20% have anti-Ta, and 40% have no diagnostic antibodies or uncharacterized antibodies.   (See References)

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E) anti-CV2

This answer is incorrect.


Anti-Hu antibodies are found in approximately 35% of patients with paraneoplastic limbic encephalitis. Approximately 20% have anti-Ta, and 40% have no diagnostic antibodies or uncharacterized antibodies.  (See References)

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References:

1. Gultekin, S.H., Rosenfeld, M.R., Voltz, R., Eichen, J., Posner, J.B., and Dalmau, J. (2000). "Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients." Brain, 123 ( Pt 7) 1481-94. (PMID:10869059)
2. Dalmau, J.O., and Posner, J.B. (1999). "Paraneoplastic syndromes." Arch Neurol, 56(4) 405-8. (PMID:10199327)
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adult
Paraneoplastic Syndromes 01
Question ID: 010608154
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 01/06/2008
Modified: 01/06/2008
Estimated Permutations: 25200

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