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Narcolepsy 01

Topic: Adult

Created on Tuesday, October 16 2007 by jdmiles

Last modified on Tuesday, October 16 2007.

Narcolepsy is associated with a deficiency of which of the following substances?


 
        A) Orexin
 
        B) Caffeine
 
        C) Somatostatin
 
        D) Vasopressin
 
        E) Uracretin
 

 


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This question was created on October 16, 2007 by jdmiles.
This question was last modified on October 16, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) orexin

This answer is correct.


A deficiency of orexin (also called hypocretin) is associated with narcolepsy.

  (See References)

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B) caffeine

This answer is incorrect.


A deficiency of orexin (also called hypocretin) is associated with narcolepsy.

  (See References)

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C) somatostatin

This answer is incorrect.


A deficiency of orexin (also called hypocretin) is associated with narcolepsy.

  (See References)

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D) vasopressin

This answer is incorrect.


A deficiency of orexin (also called hypocretin) is associated with narcolepsy.

  (See References)

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E) uracretin

This answer is incorrect.


A deficiency of orexin (also called hypocretin) is associated with narcolepsy.

  (See References)

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References:

1. Mieda, M., and Yanagisawa, M. (2002). "Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors." Curr Opin Neurobiol, 12(3) 339-45. (PMID:12049942)
2. Sakurai, T. (2006). "Roles of orexins and orexin receptors in central regulation of feeding behavior and energy homeostasis." CNS Neurol Disord Drug Targets, 5(3) 313-25. (PMID:16787231)
3. Rodgers, R.J., Ishii, Y., Halford, J.C., and Blundell, J.E. (2002). "Orexins and appetite regulation." Neuropeptides, 36(5) 303-25. (PMID:12450737)
4. Székely, M., Pétervári, E., Balaskó, M., Hernádi, I., and Uzsoki, B. (2002). "Effects of orexins on energy balance and thermoregulation." Regul Pept, 104(1-3) 47-53. (PMID:11830276)
5. Siegel, J.M. (1999). "Narcolepsy: a key role for hypocretins (orexins)" Cell, 98(4) 409-12. (PMID:10481905)
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adult
Narcolepsy 01
Question ID: 101607071
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/16/2007
Modified: 10/16/2007
Estimated Permutations: 118800

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