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Optic Pathway Gliomas 01

Topic: Imaging

Created on Sunday, October 12 2008 by jdmiles

Last modified on Sunday, October 12 2008.


Regarding the tumor seen in this image, which of the following statements is most accurate?

 
        A) Tumors of this kind are seen more frequently in patients with von Hippel-Lindau disease
 
        B) Tumors of this kind are seen more frequently in patients with neurofibromatosis type 1
 
        C) Tumors of this kind are seen more frequently in patients with neurofibromatosis type 2
 
        D) Tumors of this kind are seen more frequently in patients with tuberous sclerosis
 
        E) Tumors of this kind are usually pleomorphic xanthoastrocytomas
 

 


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This question was created on October 12, 2008 by jdmiles.
This question was last modified on October 12, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Tumors of this kind are seen more frequently in patients with von Hippel-Lindau disease

This answer is incorrect.


The MRI shows an optic glioma behind the left eye. Optic pathway gliomas are a common finding in neurofibromatosis type 1 (NF1). Optic pathway gliomas are usually pilocytic astrocytomas.
Von Hippel-Lindau disease (vHL) does not typically present with an optic glioma. Radiographically visible lesions typically associated wtih vHL include hemangioblastomas, especially in the cerebellum and retina.  (See References)

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B) Tumors of this kind are seen more frequently in patients with neurofibromatosis type 1

This answer is correct.



The MRI shows an optic glioma behind the left eye. Optic pathway gliomas are a common finding in neurofibromatosis type 1 (NF1). Optic pathway gliomas are usually pilocytic astrocytomas.  (See References)

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C) Tumors of this kind are seen more frequently in patients with neurofibromatosis type 2

This answer is incorrect.


The MRI shows an optic glioma behind the left eye. Optic pathway gliomas are a common finding in neurofibromatosis type 1 (NF1). Optic pathway gliomas are usually pilocytic astrocytomas.  (See References)

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D) Tumors of this kind are seen more frequently in patients with tuberous sclerosis

This answer is incorrect.


The MRI shows an optic glioma behind the left eye. Optic pathway gliomas are a common finding in neurofibromatosis type 1 (NF1). Optic pathway gliomas are usually pilocytic astrocytomas. <br > Tuberous sclerosis (TS) does not typically present with an optic glioma. Radiographically visible lesions typically associated wtih TS include subependymal hamartomas and cortical tubers.  (See References)

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E) Tumors of this kind are usually pleomorphic xanthoastrocytomas

This answer is incorrect.


The MRI shows an optic glioma behind the left eye. Optic pathway gliomas are a common finding in neurofibromatosis type 1 (NF1). Optic pathway gliomas are usually pilocytic astrocytomas.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)Advertising:
2. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York. (ISBN:0070674973)Advertising:
3. Santos, C.C., Miller, V.S., and Roach, E.S. (2004). Neurocutaneous syndromes. In Bradley, W.G., Daroff, R.B., Fenichel, G.M., and Jankovic, J. (Eds.). Neurology in Clinical Practice, Fourth Edition. Butterworth Heinemann, Philadelphia, pp. 1867-1900 (ISBN:0750674695).Advertising:
4. Rowland, L.P. (Ed) (2000). Merritt's Neurology, 10th Edition. Lippincott Williams & Wilkins, Philadelphia. (ISBN:0683304747)Advertising:
5. Fenichel, G.M. (2005). Clinical Pediatric Neurology, 5th ed. Elsevier, Philadelphia. (ISBN:1416001697)Advertising:
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imaging
Optic Pathway Gliomas 01
Question ID: 101208162
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/12/2008
Modified: 10/12/2008
Estimated Permutations: 8400

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