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Infections 01

Topic: Pathology

Created on Saturday, February 7 2009 by gliageek

Last modified on Saturday, February 7 2009.


Courtesy of Dr. Mark Cohen

Which of the following fungal organisms is most likely to result in this gross appearance?

 
        A) Cryptococcus neoformans
 
        B) Coccidiodes immitus
 
        C) Aspergillus fumigatus
 
        D) Candida albicans
 
        E) Zygomycetes
 

 


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This question was created on February 07, 2009 by gliageek.
This question was last modified on February 07, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Cryptococcus neoformans

This answer is incorrect.


Cryptococcus neoformans causes chronic meningitis in patients with impaired T-cell immunity.  (See References)

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B) Coccidiodes immitus

This answer is incorrect.


Coccidiodes immitus causes meningitis in a subset of patients with pulmonary disease acquired in the region of the San Joachin valley  (See References)

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C) Aspergillus fumigatus

This answer is correct.


Multiple foci of hemorrhagic necrosis are typically seen in CNS aspergillosis.  (See References)

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D) Candida albicans

This answer is incorrect.


Candida albicans usually manifests as multiple cortical microabscesses, and is often seen in critically ill infants receiving TPN. An example of cerebral candidiasis is shown in the image below:

Courtesy of Dr. Mark Cohen
  (See References)

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E) Zygomycetes

This answer is incorrect.


Zygomycetes infection (mucormycosis) typically results in hemorrhagic necrosis adjacent to the cribiform plate.  (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
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pathology
Infections 01
Question ID: 020709181
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/07/2009
Modified: 02/07/2009
Estimated Permutations: 120

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