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NeurOnc 02

Topic: Pathology

Created on Sunday, February 8 2009 by gliageek

Last modified on Sunday, February 8 2009.


Courtesy of Dr. Mark Cohen

This pattern of tumor spread is most characteristic of which of the following tumors?

 
        A) Astrocytoma
 
        B) Dysembryoplastic neuroepithelial tumor
 
        C) Ganglioglioma
 
        D) Primary CNS lymphoma
 
        E) Oligodendroglioma
 

 


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This question was created on February 08, 2009 by gliageek.
This question was last modified on February 08, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) astrocytoma

This answer is incorrect.


Astrocytic tumors don't easily permeate into grey matter  (See References)

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B) dysembryoplastic neuroepithelial tumor

This answer is incorrect.


The "specific glioneuronal component" of DNT is composed of oligodendroglial-like cells containing morphologically normal neurons NOT tightly surrounded by the OLCs.  (See References)

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C) ganglioglioma

This answer is incorrect.


As is typical for grade I tumors, gangliogliomas do not infiltrate adjacent cortical tissue  (See References)

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D) primary CNS lymphoma

This answer is incorrect.


PCNSLs classicaly show perivascular growth, but NOT perineuronal accumulation  (See References)

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E) oligodendroglioma

This answer is correct.


Perivascular and perineuronal satellitosis is characteristic of oligodendroglioma spread into grey matter  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582)Advertising:
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pathology
NeurOnc 02
Question ID: 020809067
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/08/2009
Modified: 02/08/2009
Estimated Permutations: 120

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