Have you seen the parietal watch?

Infections 02

Topic: Pathology

Created on Sunday, February 8 2009 by gliageek

Last modified on Sunday, February 8 2009.


Courtesy of Dr. Mark Cohen

Cowdry B inclusions, similar to those shown here, were initially felt to be diagnostic of which of the following?

 
        A) Poliomyelitis
 
        B) Rabies encephalitis
 
        C) Herpes simplex encephalitis
 
        D) Subacute sclerosing panencephalitis
 
        E) Cytomegalovirus encephalitis
 

 


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This question was created on February 08, 2009 by gliageek.
This question was last modified on February 08, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Poliomyelitis

This answer is correct.


"Ground-glass" intranuclear inclusions were identified within anterior horn cell neurons in patients with poliomyelitis.  (See References)

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B) rabies encephalitis

This answer is incorrect.


Cytoplasmic inclusions (Negri or lyssa bodies) may be identified within hippocampal pyramidal and cerebellar Purkinje neurons  (See References)

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C) herpes simplex encephalitis

This answer is incorrect.


Cowdry A type inclusions may be identified during the second week of infection  (See References)

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D) Subacute sclerosing panencephalitis

This answer is incorrect.


Cowdry A intranuclear measles inclusions characterise this progressive neurologic infection  (See References)

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E) cytomegalovirus encephalitis

This answer is incorrect.


CMV encephalitis is characterised by enlaqrged cells with Cowdry A intranuclear inclusions and PAS+ intracytoplasmic inclusions  (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
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pathology
Infections 02
Question ID: 020809090
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/08/2009
Modified: 02/08/2009
Estimated Permutations: 120

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