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Infections 05

Topic: Pathology

Created on Friday, February 13 2009 by gliageek

Last modified on Saturday, February 21 2009.


Courtesy of Dr. Mark Cohen
The appearance of these cells is diagnostic of infection with which of the following viruses?

 
        A) Herpes simplex virus
 
        B) JC virus
 
        C) Cytomegalovirus
 
        D) Rabies
 
        E) Measles (Subacute sclerosing panencephalitis)
 

 


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This question was created on February 13, 2009 by gliageek.
This question was last modified on February 21, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Herpes simplex virus

This answer is incorrect.


Intranuclear inclusions without cytoplasmic inclusions or cellular enlargement   (See References)

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B) JC virus

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Cowdry B-like inclusions within astrocytes and oligodendroglial cells   (See References)

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C) Cytomegalovirus

This answer is correct.


The combination of cellular enlargement with both intranuclear and intracytoplasmic inclusions is diagnostic of CMV infection   (See References)

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D) Rabies

This answer is incorrect.


Cytoplasmic inclusions in hippocampal neurons and Purkinje cells   (See References)

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E) Measles (Subacute sclerosing panencephalitis)

This answer is incorrect.


Intranuclear inclusions without cytoplasmic inclusions or cellular enlargement   (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313) Advertising:
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pathology
Infections 05
Question ID: 021309184
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/13/2009
Modified: 02/21/2009
Estimated Permutations: 120

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