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Neuromuscular 04

Topic: Pathology

Created on Saturday, February 14 2009 by gliageek

Last modified on Saturday, February 21 2009.


Courtesy of Dr. Mark Cohen
These strongly NADH-TR positive structures may be seen in which of the following conditions?

 
        A) Periodic paralysis
 
        B) Nemaline myopathy
 
        C) Myotonic dystrophy
 
        D) Malignant hyperthermia
 
        E) Myofibrillary myopathy
 

 


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This question was created on February 14, 2009 by gliageek.
This question was last modified on February 21, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Periodic paralysis

This answer is correct.


Tubular aggregates may be seen in some of the periodic paralyses   (See References)

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B) Nemaline myopathy

This answer is incorrect.


The thread shaped inclusions seen on trichrome and by EM do not react with NADH-TR   (See References)

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C) Myotonic dystrophy

This answer is incorrect.


NADH-TR often demonstrates ring fibers in myotonic dystrophy   (See References)

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D) Malignant hyperthermia

This answer is incorrect.


Muscle biopsies are either normal or show minicores or central cores   (See References)

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E) Myofibrillary myopathy

This answer is incorrect.


The hyaline inclusions seen on trichrome and by EM do not react with NADH-TR   (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313) Advertising:
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pathology
Neuromuscular 04
Question ID: 021409120
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/14/2009
Modified: 02/21/2009
Estimated Permutations: 120

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