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Neurocutaneous 06

Topic: Pathology

Created on Monday, February 16 2009 by gliageek

Last modified on Monday, February 16 2009.


Courtesy of Dr. Mark Cohen
This epileptogenic lesion may also be encountered as an asymptomatic finding in which of the following diseases?

 
        A) Von Hippel-Lindau disease
 
        B) Sturge-Weber disease
 
        C) Neurofibromatosis, type 1
 
        D) Schwannomatosis
 
        E) Neurofibromatosis, type 2
 

 


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This question was created on February 16, 2009 by gliageek.
This question was last modified on February 16, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) von Hippel-Lindau disease

This answer is incorrect.


Meningeal hemangioblastoma may be seen in vHLD  (See References)

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B) Sturge-Weber disease

This answer is incorrect.


SWD shows meningeal angiomatosis with associated cortical calcification  (See References)

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C) Neurofibromatosis, type 1

This answer is incorrect.


Meningioangiomatosis is NOT part of NF1, although included as part of VRD in older literature (before molecular separation of NF1 and NF2)  (See References)

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D) Schwannomatosis

This answer is incorrect.


Does not include meningioangiomatosis  (See References)

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E) Neurofibromatosis, type 2

This answer is correct.


For reasons which are not at all clear, meningioangiomatosis in NF2 is nearly always asymptomatic, even when multiple  (See References)

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References:

1. Love, S., Louis, D.N., and Ellison, D.W. (2008). Greenfield's Neuropathology, 8th Edition. Oxford University Press, USA (ISBN:0340906820)Advertising:
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pathology
Neurocutaneous 06
Question ID: 021609113
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/16/2009
Modified: 02/16/2009
Estimated Permutations: 120

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