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Neurocutaneous 08

Topic: Pathology

Created on Monday, February 16 2009 by gliageek

Last modified on Monday, February 16 2009.


Courtesy of Dr. Mark Cohen
This is the most common nervous system tumor in which of the following syndromes?

 
        A) Cowden disease
 
        B) Gorlin syndrome
 
        C) Carney complex
 
        D) APC-related Turcot syndrome
 
        E) Li-Fraumeni
 

 


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This question was created on February 16, 2009 by gliageek.
This question was last modified on February 16, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Cowden disease

This answer is incorrect.


Dysplastic gangliocytoma of cerebellum  (See References)

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B) Gorlin syndrome

This answer is incorrect.


Medulloblastoma, usually desmoplastic  (See References)

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C) Carney complex

This answer is incorrect.


Psammomatous melanotic schwannoma  (See References)

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D) APC-related Turcot syndrome

This answer is incorrect.


Medulloblastomas are more common than GBMs  (See References)

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E) Li-Fraumeni

This answer is correct.


70% of nervous system tumors in Li-Fraumeni are infiltrating gliomas; ~20% are medulloblastomas  (See References)

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References:

1. Love, S., Louis, D.N., and Ellison, D.W. (2008). Greenfield's Neuropathology, 8th Edition. Oxford University Press, USA (ISBN:0340906820)Advertising:
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pathology
Neurocutaneous 08
Question ID: 021609120
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/16/2009
Modified: 02/16/2009
Estimated Permutations: 120

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