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Pathology in Ischemic Stroke 02

Topic: Pathology

Created on Saturday, February 24 2007 by jdmiles

Last modified on Saturday, February 24 2007.

A patient presents with an acute ischemic stroke and dies 1 week later. Of the following choices, which is most likely to be seen on pathological examination of the brain at autopsy?

 
        A) Eosinophilic changes in neurons
 
        B) Reactive astrocytes at the edge of the infarct
 
        C) Tissue pallor
 
        D) Gliotic scar at infarct edges
 
        E) Acute neuronal necrosis
 

 


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This question was created on February 24, 2007 by jdmiles.
This question was last modified on February 24, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) eosinophilic changes in neurons

This answer is incorrect.


Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke.  (See References)

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B) reactive astrocytes at the edge of the infarct

This answer is correct.


Appearance of macrophages, capillary proliferation, and the appearance of reactive astrocytes at the edge of the infarct occur 2 days to 2 weeks after the infarct.  (See References)

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C) tissue pallor

This answer is incorrect.


Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke.  (See References)

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D) gliotic scar at infarct edges

This answer is incorrect.


Appearance of cavitation, liquefaction necrosis, and the formation of a glial scar at the edge of the infarct occur months to years after the infarct.  (See References)

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E) acute neuronal necrosis

This answer is incorrect.


Tissue pallor, acute neuronal necrosis, and eosinophilic changes in neurons are seen 12-24 hours after an acute ischemic stroke.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier, Philadelphia.
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pathology
Pathology in Ischemic Stroke 02
Question ID: 022407198
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 02/24/2007
Modified: 02/24/2007
Estimated Permutations: 5400

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