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Intraneuronal Inclusions 01

Topic: Pathology

Created on Sunday, January 18 2009 by jdmiles

Last modified on Sunday, January 18 2009.


In the image above, note the structure indicated by the unnecessarily large green arrow.
What substance is the primary constituent of this structure?

 
        A) Synuclein
 
        B) Amyloid
 
        C) Nougat
 
        D) Tau
 
        E) Actin
 

 


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This question was created on January 18, 2009 by jdmiles.
This question was last modified on January 18, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) synuclein

This answer is correct.


The big pink blob in this image is a Lewy body.
Lewy bodies are intranuclear inclusions comprised primarily of alpha-synuclein.   (See References)

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B) amyloid

This answer is incorrect.


Amyloid is a major component of senile plaques.
However, it is not a component of the structure shown above.   (See References)

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C) nougat

This answer is incorrect.


Nougat is a major component of the inclusions found in many candy bars.
However, it is not a component of the structure shown above.   (See References)

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D) tau

This answer is incorrect.


Tau protein is a major component of Pick bodies and neurofibrillary tangles.
However, it is not a component of the structure shown above.   (See References)

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E) actin

This answer is incorrect.


Actin is a major component of Hirano bodies.
However, it is not a component of the structure shown above.   (See References)

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References:

1. Rowland, L.P. (Ed) (2000). Merritt's Neurology, 10th Edition. Lippincott Williams & Wilkins, Philadelphia. (ISBN:0683304747) Advertising:
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pathology
Intraneuronal Inclusions 01
Question ID: 111508139
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 01/18/2009
Modified: 01/18/2009
Estimated Permutations: 240

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