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Muscle Fiber Histology 02

Topic: Pathology

Created on Thursday, December 20 2007 by jdmiles

Last modified on Thursday, December 20 2007.

This photomicrograph shows a cytochrome C oxidase stain of skeletal muscle. In normal muscle, which of the following statements is true about the fibers that stain DARKER with cytochrome C oxidase?

 
        A) They contract more rapidly than the lighter fibers
 
        B) There is no functional difference between cells that stain differently
 
        C) They are type 2 fibers
 
        D) They have a more anaerobic metabolism compared to the lighter fibers
 
        E) They have a more oxidative metabolism compared to the lighter fibers
 

 


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This question was created on December 20, 2007 by jdmiles.
This question was last modified on December 20, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) They contract more rapidly than the lighter fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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B) There is no functional difference between cells that stain differently

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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C) They are type 2 fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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D) They have a more anaerobic metabolism compared to the lighter fibers

This answer is incorrect.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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E) They have a more oxidative metabolism compared to the lighter fibers

This answer is correct.


Cytochrome C oxidase is a marker of mitochondrial activity. In normal muscle, type 1 fibers stain darker than type 2 fibers with this type of stain.
Type 1 fibers tend to contract more slowly. They are more fatigue resistant, and have a more oxidative metabolism than type 2 fibers.
Type 2 fibers are faster, more easily fatigued, and their metabolism tends to be more anaerobic (glycolytic) compared to type 1 fibers.  (See References)

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References:

1. Prayson, R.A., and Goldblum, J.R. (Eds.) (2005). Neuropathology. Elsevier Churchill Livingstone, Philadelphia. (ISBN:0443066582) Advertising:
2. Kandel, E.R., Schwartz, J.H., and Jessel, T.M. (2000). Principles of Neural Science, 4th ed. McGraw-Hill, New York. (ISBN:0838577016)Advertising:
3. / Alan Stevens, James Lowe. . London : Gower , 1992 (ISBN:0397446330)
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pathology
Muscle Fiber Histology 02
Question ID: 122007037
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/20/2007
Modified: 12/20/2007
Estimated Permutations: 360

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