antiepileptic medications

Topic: Pathology

Created on Saturday, September 2 2006 by

Last modified on Saturday, September 2 2006.

 
        A) Tiagabine has no known significant drug interactions.
 
        B) Ethosuximide is a glutamate receptor antagonist.
 
        C) Ethosuximide is approved as adjunct therapy only.
 
        D) Ethosuximide is indicated for tonic-clonic.
 
        E) Felbamate is indicated for treatment of Lennox-Gastaut syndrome.
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on September 02, 2006 by .
This question was last modified on September 02, 2006.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) Tiagabine has no known significant drug interactions.

This answer is incorrect.

The statement, "Tiagabine has no known significant drug interactions." is false.
Tiagabine causes reduction of sodium currents, is indicated for treatment of partial seizures, is metabolized primarily in the liver, and is approved as adjunct therapy only.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) Ethosuximide is a glutamate receptor antagonist.

This answer is incorrect.

The statement, "Ethosuximide is a glutamate receptor antagonist." is false.
Ethosuximide causes reduction of T-Calcium currents, is indicated for treatment of absence seizures, is metabolized primarily in the liver, induces hepatic enzymes, has leukopenia as a relatively common side effect, has no known significant drug interactions, has no known significant interactions with other AEDs, and is the drug of first choice for patients with absence seizures only.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) Ethosuximide is approved as adjunct therapy only.

This answer is incorrect.

The statement, "Ethosuximide is approved as adjunct therapy only." is false.
Ethosuximide causes reduction of T-Calcium currents, is indicated for treatment of absence seizures, is metabolized primarily in the liver, induces hepatic enzymes, has leukopenia as a relatively common side effect, has no known significant drug interactions, has no known significant interactions with other AEDs, and is the drug of first choice for patients with absence seizures only.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) Ethosuximide is indicated for tonic-clonic.

This answer is incorrect.

The statement, "Ethosuximide is indicated for tonic-clonic." is false.
Ethosuximide causes reduction of T-Calcium currents, is indicated for treatment of absence seizures, is metabolized primarily in the liver, induces hepatic enzymes, has leukopenia as a relatively common side effect, has no known significant drug interactions, has no known significant interactions with other AEDs, and is the drug of first choice for patients with absence seizures only.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) Felbamate is indicated for treatment of Lennox-Gastaut syndrome.

This answer is correct.

The statement, "Felbamate is indicated for treatment of Lennox-Gastaut syndrome." is true.
Felbamate is indicated for treatment of Lennox-Gastaut syndrome.  (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Browne, T.R., & Holmes, G.L. (2004). Handbook of Epilepsy, 3rd Edition. Lippincott Williams & Wilkins, Philadelphia., Leppik, I.E. (2001). Contemporary Diagnosis and Management of the Patient with Epilepsy, 5th Edition. Handbooks in Health Care, Newtown, Pennsylvania.

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
pathology
antiepileptic medications
Question ID: 540025025
Question written by . (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 09/02/2006
Modified: 09/02/2006
Estimated Permutations: 0