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Bad Seafood 01

Topic: Pharmacology

Created on Saturday, October 18 2008 by jdmiles

Last modified on Saturday, October 18 2008.

A 56 year-old dandelion cleaner is in excellent health, until he pops into a local seafood restaurant and eats obscene amounts of seafood. Then he develops an acute neuropathy. Which of the following substances is most likely responsible for in this man's illness?

 
        A) Mercury
 
        B) Trichloroethylene
 
        C) Carbon monoxide
 
        D) Alpha-bungarotoxin
 
        E) Ciguatoxins
 

 


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This question was created on October 18, 2008 by jdmiles.
This question was last modified on October 18, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Mercury

This answer is incorrect.


While mercury can be found in seafood, it would be quite unusual for someone to develop acute mercury toxicityfrom eating seafood.   (See References)

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B) Trichloroethylene

This answer is incorrect.


It would be unusual for our patient to have developed acute trichloroethylene toxicity from eating seafood. Further, narcosis would be a more typical presentation of acute trichloroethylene toxicity.   (See References)

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C) Carbon monoxide

This answer is incorrect.


Carbon monoxide is a gas at room temperature. It is not often found in toxic concentrations in seafood.   (See References)

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D) alpha-bungarotoxin

This answer is incorrect.


Alpha-bungarotoxin is not a fish toxin.   (See References)

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E) ciguatoxins

This answer is correct.


Ciguatera, caused by ciguatoxins, is the most common form of nonbacterial food poisoning in the United States and Canada. Saxitoxin is another toxin which can be found in fish. Another fish toxin is tetrodotoxin a neurotoxin found in fugu, a type of puffer fish.   (See References)

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References:

1. Rowland, L.P. (Ed) (2000). Merritt's Neurology, 10th Edition. Lippincott Williams & Wilkins, Philadelphia. (ISBN:0683304747) Advertising:
2. Kandel, E.R., Schwartz, J.H., and Jessel, T.M. (2000). Principles of Neural Science, 4th ed. McGraw-Hill, New York. (ISBN:0838577016) Advertising:
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pharmacology
Bad Seafood 01
Question ID: 101408119
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/18/2008
Modified: 10/18/2008
Estimated Permutations: 8400

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