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Hormones and Neurotransmitters and Stuff 01

Topic: Pharmacology

Created on Tuesday, October 16 2007 by jdmiles

Last modified on Tuesday, October 16 2007.

Administration of hypocretin results in which of the following?


 
        A) Decrease in appetite
 
        B) Sleepiness
 
        C) Decrease in body temperature
 
        D) Narcolepsy
 
        E) Increase in body temperature
 

 


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This question was created on October 16, 2007 by jdmiles.
This question was last modified on October 16, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Decrease in appetite

This answer is incorrect.


Administration of orexin (also called hypocretin) results in stimulation of appetite and an increase in body temperature.  A deficiency of orexin is associated with narcolepsy.

  (See References)

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B) Sleepiness

This answer is incorrect.


Administration of orexin (also called hypocretin) results in stimulation of appetite and an increase in body temperature.  A deficiency of orexin is associated with narcolepsy.

  (See References)

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C) Decrease in body temperature

This answer is incorrect.


Administration of orexin (also called hypocretin) results in stimulation of appetite and an increase in body temperature.  A deficiency of orexin is associated with narcolepsy.

  (See References)

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D) Narcolepsy

This answer is incorrect.


Administration of orexin (also called hypocretin) results in stimulation of appetite and an increase in body temperature.  A deficiency of orexin is associated with narcolepsy.

  (See References)

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E) Increase in body temperature

This answer is correct.


Administration of orexin (also called hypocretin) results in stimulation of appetite and an increase in body temperature.  A deficiency of orexin is associated with narcolepsy.

  (See References)

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References:

1. Mieda, M., and Yanagisawa, M. (2002). "Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors." Curr Opin Neurobiol, 12(3) 339-45. (PMID:12049942)
2. Sakurai, T. (2006). "Roles of orexins and orexin receptors in central regulation of feeding behavior and energy homeostasis." CNS Neurol Disord Drug Targets, 5(3) 313-25. (PMID:16787231)
3. Rodgers, R.J., Ishii, Y., Halford, J.C., and Blundell, J.E. (2002). "Orexins and appetite regulation." Neuropeptides, 36(5) 303-25. (PMID:12450737)
4. Székely, M., Pétervári, E., Balaskó, M., Hernádi, I., and Uzsoki, B. (2002). "Effects of orexins on energy balance and thermoregulation." Regul Pept, 104(1-3) 47-53. (PMID:11830276)
5. Siegel, J.M. (1999). "Narcolepsy: a key role for hypocretins (orexins)" Cell, 98(4) 409-12. (PMID:10481905)
6. Saper, C.B., Chou, T.C., and Scammell, T.E. (2001). "The sleep switch: hypothalamic control of sleep and wakefulness." Trends Neurosci, 24(12) 726-31. (PMID:11718878)
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pharmacology
Hormones and Neurotransmitters and Stuff 01
Question ID: 101607072
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 10/16/2007
Modified: 10/16/2007
Estimated Permutations: 240

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