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Adverse effects of AEDs 12

Topic: Pharmacology

Created on Saturday, December 8 2007 by jdmiles

Last modified on Saturday, December 8 2007.

Which of the following is a hallmark side effect of vigabatrin?

 
        A) Impaired cognition
 
        B) Gum hyperplasia
 
        C) Visual field defects
 
        D) Hirsutism
 
        E) Hyperammonemia
 

 


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This question was created on December 08, 2007 by jdmiles.
This question was last modified on December 08, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) impaired cognition

This answer is incorrect.


Impaired cognition is a hallmark side effect of topiramate, but is less characteristic of vigabatrin.  (See References)

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B) gum hyperplasia

This answer is incorrect.


Gum hyperplasia is a hallmark side effect of phenytoin, but is less characteristic of vigabatrin.  (See References)

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C) visual field defects

This answer is correct.


Side effects of vigabatrin include irritability, hyperactivity, visual field defects, insomnia, depression, psychosis, and blindness.  (See References)

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D) hirsutism

This answer is incorrect.


Hirsutism is a hallmark side effect of phenytoin, but is less characteristic of vigabatrin.  (See References)

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E) hyperammonemia

This answer is incorrect.


Hyperammonemia is a hallmark side effect of valproate, but is less characteristic of vigabatrin.  (See References)

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References:

1. Greenwood, R.S. (2000). "Adverse effects of antiepileptic drugs." Epilepsia, 41 Suppl 2 S42-52. (PMID:10885739)
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pharmacology
Adverse effects of AEDs 12
Question ID: 12080712
Question written by J. Douglas Miles, (C) 2006-2009, all rights reserved.
Created: 12/08/2007
Modified: 12/08/2007
Estimated Permutations: 12558000

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