FrontalCortex, Inc. is a non-profit corporation dedicated to neurology education.

An Oligo...!

Topic: Physiology

Created on Monday, October 27 2008 by rednucleus

Last modified on Monday, October 27 2008.

You are discussing the implications of CSF oligoclonal bands in various disease states and your colleague is referring to a disease that results in almost 100% detection of CSF oligoclonal bands. Which disease does your colleague mean?

 
        A) Multiple sclerosis (MS)
 
        B) Behjet's disease
 
        C) Neurosyphilis
 
        D) Neuro-lupus
 
        E) Subacute sclerosing panencephalitis (SSPE)
 

 


Back to the question = Go back to the top of the page.
See another question like this one = Reload a different version of this question ().
Click here for a random question = Load a random question from the database.
Clone this question = Use this question as a template to create a totally NEW question.
Rate this question = Enter detailed rating for this question!
Average rating not yet available
= How users like you have rated this question.
This question was created on October 27, 2008 by rednucleus.
This question was last modified on October 27, 2008.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Multiple sclerosis (MS)

This answer is incorrect.


These bands are seen in 83-94% of clinically definite multiple sclerosis. Note that CSF oligoclonal bands are not pathognomonic for MS.  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




B) Behjet's disease

This answer is incorrect.


CNS inflammatory diseases can result in oligoclonal bands, but the percentage is not that high. Other causes are neuro-sarcoidosis, Guillain-Barre, and primary CNS vasculitis.  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




C) Neurosyphilis

This answer is incorrect.


These bands are seen in around 50% of cases. Bacterial, tuberculous, spirochetal, and fungal CNS infections can produce CSF oligoclonal bands  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




D) Neuro-lupus

This answer is incorrect.


CNS inflammatory diseases can result in oligoclonal bands, but the percentage is not that high.  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




E) Subacute sclerosing panencephalitis (SSPE)

This answer is correct.


Oligoclonal bands can be found in almost 100% of cases of SSPE. Note that the bands are "oligo".i.e 2-5 in number and are found in the gamma region. A single band is commonly seen in CSFs of otherwise normal healthy individuals.  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

 

 

 

References:

1. Victor, M., and Ropper, A.H. (2001). Adams and Victor's Principles of Neurology, 7th Edition. McGraw-Hill, New York. (ISBN:0070674973)Advertising:
Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this question
Average rating not yet available
Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
physiology
An Oligo...!
Question ID: 102708098
Question written by rednucleus. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 10/27/2008
Modified: 10/27/2008
Estimated Permutations: 120

User Comments About This Question:

0 user entries
Please log in if you'd like to add a comment.