The FrontalCortex question bank is free for everyone, everywhere.
All the time.

Inclusionology 02

Topic: Pathology

Created on Sunday, February 8 2009 by gliageek

Last modified on Sunday, February 8 2009.


Courtesy of Dr. Mark Cohen

This intracytoplasmic inclusion may be seen in all of the following diseases, EXCEPT:

 
        A) Frontotemporal degeneration
 
        B) Corticobasal degeneration
 
        C) Progressive supranuclear palsy
 
        D) Alzheimer disease
 
        E) Multiple system atrophy
 

 


Back to the question = Go back to the top of the page.
See another question like this one = Reload a different version of this question ().
Click here for a random question = Load a random question from the database.
Clone this question = Use this question as a template to create a totally NEW question.
Rate this question = Enter detailed rating for this question!
Average user rating for this question = 5 = How users like you have rated this question.
This question was created on February 08, 2009 by gliageek.
This question was last modified on February 08, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Frontotemporal degeneration

This answer is incorrect.


Tau-associated FTD is characterised by NFTs, often in the absence of amyloid  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




B) Corticobasal degeneration

This answer is incorrect.


Originally named "corticobasal bodies", NFTs are commonly seen in brainstem nuclei in CBD  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




C) Progressive supranuclear palsy

This answer is incorrect.


NFTs generally seen in subthalamic, pallidal,dentate, nigra, LC, and nucleus basalis of Meynert (pictured here)  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




D) Alzheimer disease

This answer is incorrect.


The distribution of NFTs is the basis for Braak staging of AD  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 




E) Multiple system atrophy

This answer is correct.


MSA is characterised by synuclein-positive inclusions within glial cells  (See References)

Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

 

 

 

References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
Back to the questionSee another question like this oneClick here for a random questionClone this question Rate this questionAverage user rating for this question = 5
Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review
pathology
Inclusionology 02
Question ID: 020809085
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/08/2009
Modified: 02/08/2009
Estimated Permutations: 120

User Comments About This Question:

0 user entries
Please log in if you'd like to add a comment.