There are 486 questions on various topics in Neurology in the FrontalCortex neurology question bank.

Infections 08

Topic: Pathology

Created on Saturday, February 14 2009 by gliageek

Last modified on Saturday, February 14 2009.


Courtesy of Dr. Mark Cohen
The best diagnosis for this myelin stained section is?

 
        A) Acute disseminated encephalomyelitis
 
        B) West nile virus encephalitis
 
        C) Progressive multifocal leukoencephalopathy
 
        D) Multiple sclerosis
 
        E) Subacute sclerosing panencephalitis
 

 


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This question was created on February 14, 2009 by gliageek.
This question was last modified on February 14, 2009.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS




A) Acute disseminated encephalomyelitis

This answer is incorrect.


Perivenular demyelination, without confluent lesions  (See References)

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B) West nile virus encephalitis

This answer is incorrect.


WNV involves deep gray matter and spinal cord, and does not primarily cause demyelination  (See References)

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C) Progressive multifocal leukoencephalopathy

This answer is correct.


PML causes confluent demyelinating lesions which preferentially affect gray-white junction  (See References)

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D) Multiple sclerosis

This answer is incorrect.


More discrete, circumscribed lesions preferentially affecting periventricular white matter  (See References)

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E) Subacute sclerosing panencephalitis

This answer is incorrect.


Affects both gray and white matter, but does not result in demyelinating lesions  (See References)

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References:

1. Graham, D.I., and Lantos, P.L. (2002). Greenfield's Neuropathology, 7th ed. Arnold Press, New York. (ISBN:0340742313)Advertising:
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pathology
Infections 08
Question ID: 021409062
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/14/2009
Modified: 02/14/2009
Estimated Permutations: 120

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