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Alexander disease, coronal section, close-up view

Last updated on Tuesday, March 24 2009 by gliageek

Alexander disease, coronal section, close-up view

Diffuse loss of white matter without sparing of subcortical U fibers

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Alexander disease, coronal section, close-up view, highlighted

Alexander disease, coronal section, close-up view, highlighted
This is a slice of brain from a patient who had Alexander disease. In this disease, there is diffuse loss of white matter. In this image, note how dark the demyelinated white matter appears, especially in contrast to the relatively spared region indicated by the unnecessarily large red arrow...

Krabbe Sparing U Fibers Coronal

Krabbe Sparing U Fibers Coronal
For comparison, loss of white matter with sparing of subcortical U fibers

Pelizaeus Merzbacher Coronal Close Up

Pelizaeus Merzbacher Coronal Close Up
For comparison, loss of white matter with sparing of subcortical U fibers

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