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Krabbe disease, H&E stain x 100

Last updated on Tuesday, March 24 2009 by gliageek

Krabbe disease, H&E stain x 100

Diffuse reactive astrocytosis with globoid cells in various stages of development

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Krabbe disease, H&E stain x 100 with arrow

Krabbe disease, H&E stain x 100 with arrow
There are many globoid cells visible in this H&E-stained specimen of brain from a person who had Krabbe disease. Krabbe disease is also called globoid cell leukodystrophy because these cells are a hallmark feature of the disease. The unnecessarily large green arrow points to one of the globoid cells.

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