There are 486 questions on various topics in Neurology in the FrontalCortex neurology question bank.

Congenital Fiber Type Disproportion

Last updated on Tuesday, April 28 2009 by gliageek

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The defining feature of congenital fiber type disproportion (CFTD) is type 1 muscle fibers which are at least 12% smaller than type 2 muscle fibers.

 

CNS abnormalities and developmental delay may be present.

 

Severity of clinical weakness correlates with smallness of type 1 fibers.

 

Most cases are sporadic.

 

 

 

References:

Katirji, B., Kaminsky, H.J., Preston, D.C., Ruff, R.L., and Shapiro, B.E. (Eds.) (2002). Neuromuscular Disorders in Clinical Practice. Butterworth Heinemann, Boston. (ISBN:0750671696)  Pp. 1114-1127.

 


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