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Glioblastoma multiforme demonstrating pseudopalisading Necrosis H&E stain x 400

Last updated on Friday, April 3 2009 by gliageek

Glioblastoma multiforme demonstrating pseudopalisading Necrosis H&E stain x 400

H&E preparation of a GBM, showing pseudopalisading necrosis.

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Pseudopalisading Necrosis Explained

Pseudopalisading Necrosis Explained
`Palisading` is when cells line up next to each other, like slats in a picket fence. These rapidly proliferating tumor cells (area outlined in green) appear to palisade around the central pale area, which represents necrotic tissue (region shaded in yellow)...

Normal brain for comparison

Normal brain for comparison
Bodian stain preparation of normal brain for comparison.

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