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Vanishing white matter disease

Last updated on Tuesday, March 24 2009 by gliageek

Vanishing white matter disease

Chromatolytic appearing neurons within cerebral cortex

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Vanishing white matter disease

Vanishing white matter disease
The neurons outlined in green are chromatolytic. Chromatolytic neurons are pale and swollen in reaction to axonal injury. Axonal injury may occur in demyelinating disease secondary to the loss of myelin.

For Comparison, Normal Neuropil

For Comparison, Normal Neuropil
This is an H&E-stained section of normal neuropil. Compare the normal neurons in this image to the chromatolytic neurons in the image of VWMD.

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