Basic Neuropathology 8

Topic:

Created on Thursday, February 14 2013 by gliageek

Last modified on Thursday, February 14 2013.

 
        A) Progressive multifocal leukoencephalopathy
 
        B) Alzheimer's disease
 
        C) Parkinson's disease
 
        D) Rabies encephalitis.
 
        E) Jakob-Creutzfeldt disease
 

 

	= Go back to the top of the page.
	= Reload a different version of this question ().
	= Load a random question from the database.
	= Use this question as a template to create a totally NEW question.
	= Enter detailed rating for this question!
	= How users like you have rated this question.

This question was created on February 14, 2013 by gliageek.
This question was last modified on February 14, 2013.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ANSWERS AND EXPLANATIONS

---

A) Progressive multifocal leukoencephalopathy

This answer is incorrect.

Progressive multifocal leukoencephalopathy is characterized by intranuclear inclusions within astrocytes and oligodendroglial cells.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

B) Alzheimer's disease

This answer is incorrect.

Patients with Alzheimer's disease may show immunoreactivity for amyloid within the cerebellar molecular layer, but do not show plaques within the cerebellar granule cell layer. In addition, senile plaques in Alzheimer disease do not show peripheral radiations.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

C) Parkinson's disease

This answer is incorrect.

Lewy bodies are intracytoplasmic inclusions.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

D) Rabies encephalitis.

This answer is incorrect.

In patients with rabies encephalitis, Negri (or lyssa) bodies may be seen within the cytoplasm Of Purkinje cells.  (See References)

Please log in if you want to rate questions.

 

 

 

 

 

 

 

 

 

---

E) Jakob-Creutzfeldt disease

This answer is correct.

About 10% of patients with sporadic Jakob-Creutzfeldt disease will show kuru plaques within the cerebellar granule cell layer  (See References)

Please log in if you want to rate questions.

 

 

 

 

References:

1. Krasnianski, A., Schulz-Schaeffer, W.J., Kallenberg, K., Meissner, B., Collie, D.A., Roeber, S., Bartl, M., Heinemann, U., Varges, D., Kretzschmar, H.A., and Zerr, I. (2006). "Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD." Brain, 129(Pt 9) 2288-96. (PMID:16720682)
2. Sikorska, B., Knight, R., Ironside, J.W., and Liberski, P.P. (2012). "Creutzfeldt-Jakob disease." Adv Exp Med Biol, 724 76-90. (PMID:22411235)

Please log in if you want to rate questions.

 

FrontalCortex.com -- Neurology Review Questions -- Neurology Boards -- Board Review -- Residency Inservice Training Exam -- RITE Exam Review

Basic Neuropathology 8
Question ID: 021413097
Question written by gliageek. (C) FrontalCortex.com 2006-2009, all rights reserved. Created: 02/14/2013
Modified: 02/14/2013
Estimated Permutations: 120